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Terpene Isolates 101: Guaiol

If you're just getting started with terpenes, odds are you're wondering how each isolate can be used. Terpene isolates can be used in hemp, CBD, and cannabis products as well as concentrates, vapes, foods, beverages, and aromatherapy infusions. In fact, adding terpenes to health and beauty products, cosmetics, vaporizers, foods and beverages, and aromatherapy infusions is a great way to add an extra boost of body-nourishing benefits to your products and make THC/CBD products more effective. This week, we're diving deeper into the anti-inflammatory and pine-scented terpene isolate known as Guaiol (pronounced g-why-ee-ol).

cypress trees contain high concentrations of guaiol terpenes

Guaiol Terpene Isolate

When you think of piney terpenes, you probably think of pinene since it’s one of the most prevalent and extensively studied terpenes found in cannabis. However, it’s lesser-known cousin Guaiol also shows up (in small amounts) in cannabis strains and offers similar effects, therapeutic benefits, and of course, potent pine flavors!


However, Guaiol is different from most other terpenes. While most terpenes are oil-based, Guaiol is most commonly found in timber - specifically evergreens and cypress pine. Its unique piney scent and antibacterial properties make it a great choice in a variety of industries, including medicine, food and beverage, cosmetics, and perfumes.


Guaiol is usually derived from the guaiacum plant, which is an evergreen tree from the tropics that has been used in natural medicine extensively since the 16th century. Around the mid-1700s, Guaiol was extracted from the dense, oily wood of the guaiacum tree and used to treat syphilis, sore throats, gout, and arthritis for its systemic anti-inflammatory properties.


This systemic anti-inflammatory effect makes it a potentially effective treatment for hundreds of conditions and diseases, including fibromyalgia and cancer. However, further study still needs to be conducted on Guaiol terpenes to rule out possible complications as a supplement. Always check with your doctor before starting any supplementation or health regimen, even with naturally occurring terpenes.


Benefits of Guaiol Terpene Isolate

While research on Guaiol terpenes is mostly limited, we do have a fair amount of anecdotal evidence and a handful of scientific studies conducted on Guaiol and the plants it’s extracted from. For starters, Guaiol, like most terpenes, is best known for its anti-microbial and anti-inflammatory effects.


However, it’s anti-inflammatory effect is different than the majority of terpenes because it’s a systemic anti-inflammatory. This allows the anti-inflammatory effect to work through the body in all of its systems versus in one isolated place. It reduces inflammation in the lungs to treat coughing as well as in your limbs and other organs, making it above average at treating inflammatory conditions as diverse as arthritis, constipation, gout, sore throat, and even syphilis. As we mentioned before, Guaiol terpenes have been used this way since the 16th century.

guaiol terpenes can be found in pine trees

Interestingly, Guaiol is also a diuretic. It can lower blood pressure and act as an antioxidant to a similar degree as some other terpenes and major cannabinoids like THC and CBD. Together with the anti-inflammatory effect, Guaiol showcases efficiency as a potent analgesic or painkiller.


When used with other terpenes, Guaiol has shown its ability to kill intestinal parasites. In a similar study, it also displayed potent antioxidant properties. It can also be used as an insect repellent when used with other terpenes, such as terpinolene or citronellol.


In rodent models, Guaiol was also able to strengthen the effects of chemotherapy and potentially reduce tumors. It can cause cancer and tumor cells to follow through with apoptosis, or programmed cell death. A similar study highlighted Guaiol as a potent anti-fungal and antibacterial agent.


All in all, Guaiol shows potential as a source of holistic medicine. However, further study is still needed to fully understand the effects of Guaiol terpenes.


Natural Sources of Guaiol Terpene Isolate

Guaiol, while not a primary terpene, is found in a pretty good ratio in many cannabis strains like Golden Pineapple, Chernobyl, and Agent Orange. While it doesn’t exist naturally in a lot of plants, it can usually be found in dense, oily trees like cypress pine and guaiacum, which is a tropical evergreen tree. You can also find Guaiol in ginger, ginseng, and valerian.

TLDR; Guaiol Terpenes

  • Anti-inflammatory

  • Anti-parasitic

  • Antibacterial

  • Antifungal

  • Antiviral

  • Antimicrobial

  • Antioxidant

  • Analgesic (pain-relieving)

  • Causes apoptosis in cancer cells

  • Insecticide

  • Lowers blood pressure (diuretic)

Common Uses of Guaiol Terpenes

Whether through your favorite fruits and herbs or through a diffuser, Guaiol isolate smells and tastes great and works wonders within your body.

Guaiol terpenes can be safely added to all sorts of products to kill bacteria, reduce inflammation, and lower blood pressure. It can safely be eaten, drank, infused, and inhaled with a little bit of mixing. It can also be used to improve cannabis products like vapes and concentrates that may have lost cannabinoid potency or terpene content during extraction.

Guaiol terpene isolate for sale by peak supply co

Add Guaiol terpenes to foods and beverages to enjoy the antioxidant and antibacterial properties within the whole body. A dash of water-soluble Guaiol terpenes in your favorite foods or beverages adds an herbal pine flavor that can help reduce pain and inflammation, reduce oxygen in the blood, and lower your blood pressure.

Add Guaiol terpenes to essential oil diffusers and aromatherapy infusions to kill airborne bacteria, viruses, and fungal spores and improve indoor air quality. The pine aroma is also great for promoting calm and relaxation and helping you get to sleep.

Add Guaiol terpenes to cannabis concentrates and hemp oils made from strains with higher Guaiol terpene content, such as ACDC, Cinex, or Plushberry. Try it in products made from strains like Pennywise or Jillybean. Guaiol terpenes can make them smell and taste better and boost the potency of THC/CBD effects.

Just keep in mind that not all terpenes are created equal. Different terpenes will always have different effects, but they're not all made the same. We know you have a choice when it comes to terpene providers, but no other choice comes close to our level of quality.

At Peak Supply Co, our Guaiol terpene isolates are extracted from all-natural food-grade fruit, flower, and nut oils in our state-of-the-art facility. With our proprietary extraction and refinement method, we remove plant materials and any leftover impurities, leaving behind the purest terpene isolates on the market. Best of all, we even offer sample packs so you can try them all.

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